Evans syndrome is an autoimmune condition that presents with two or more cytopenias, which commonly includes autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP), with or without immune neutropenia.
It can be primary (or idiopathic) or secondary (i.e., associated with an underlying disorder).
When secondary, it has been associated with diseases such as systemic lupus erythematosus (SLE), common variable immunodeficiency (CVID) and autoimmune lymphoproliferative syndrome (ALPS) in younger patients, Non-Hodgkin's lymphoma (NHL) in patients older than 50 years and chronic lymphocytosis leukemia (CLL).
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