- Evans syndrome is an autoimmune condition that presents with two or more cytopenias, which commonly includes autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP), with or without immune neutropenia.
- It can be primary (or idiopathic) or secondary (i.e., associated with an underlying disorder).
- When secondary, it has been associated with diseases such as systemic lupus erythematosus (SLE), common variable immunodeficiency (CVID) and autoimmune lymphoproliferative syndrome (ALPS) in younger patients, Non-Hodgkin's lymphoma (NHL) in patients older than 50 years and chronic lymphocytosis leukemia (CLL).
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